Article
Host candidate gene polymorphisms and associated clearance of P. falciparum amodiaquine and fansidar resistance mutants in children less than 5 years in Cameroon.
Pathogens and global health - 1 Oct 2014
Ali Innocent Mbulli, Evehe Marie-Solange Bebandue, Netongo Palmer Masumbe, Atogho-Tiedeu Barbara, Akindeh-Nji Mbuh, Ngora Honore, Domkam Irenee Kamogne, Diakite Mahamadou, Baldip Khan, Ranford-Cartwright Lisa, Mimche Patrice Nsangou, Lamb Tracey, Mbacham Wilfred Fon
Abstract excerpt
BACKGROUND: In this post-hoc analysis, we determined the influence of single nucleotide polymorphisms in host candidate immune genes on the outcome of drug resistant malaria in Cameroon. METHODS: Human DNA from 760 patients from a previous clinical trial was subjected to mass spectrometry-based single nucleotide polymorphism (SNP) genotyping. Allele frequencies of candidate immune genes were calculated for 62...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
