Article
Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes.
PloS one - 1 Jan 2021
Tuedom Aline Gaelle Bouopda, Sarah-Matio Elangwe Milo, Moukoko Carole Else Eboumbou, Feufack-Donfack Brice Lionel, Maffo Christelle Ngou, Bayibeki Albert Ngano, Awono-Ambene Hermann Parfait, Ayong Lawrence, Berry Antoine, Abate Luc, Morlais Isabelle, Nsango Sandrine Eveline
Abstract excerpt
The spread of Plasmodium falciparum resistant parasites remains one of the major challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of molecular markers conferring resistance to different antimalarials is important to track the spread of resistant parasites and to optimize the therapeutic lifespan of current drugs. This study aimed to evaluate the prevalence of known mutations in the...
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