Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders.

doi:10.1111/j.1600-079X.2011.00902.x

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Article

Genetic variations of the melatonin pathway in patients with attention-deficit and hyperactivity disorders.

Journal of pineal research - 1 Nov 2011

Chaste Pauline, Clement Nathalie, Botros Hany Goubran, Guillaume Jean-Luc, Konyukh Marina, Pagan Cécile, Scheid Isabelle, Nygren Gudrun, Anckarsäter Henrik, Rastam Maria, Ståhlberg Ola, Gillberg I Carina, Melke Jonas, Delorme Richard, Leblond Claire, Toro Roberto, Huguet Guillaume, Fauchereau Fabien, Durand Christelle, Boudarene Lydia, Serrano Emilie, Lemière Nathalie, Launay Jean Marie, Leboyer Marion, Jockers Ralf, Gillberg Christopher, Bourgeron Thomas

Abstract excerpt

Melatonin is a powerful antioxidant and a synchronizer of many physiological processes. Alteration in melatonin signaling has been reported in a broad range of diseases, but little is known about the genetic variability of this pathway in humans. Here, we sequenced all the genes of the melatonin pathway -AA-NAT, ASMT, MTNR1A, MTNR1B and GPR50 - in 321 individuals from Sweden including 101 patients with...

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Source

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Identifiers

PMID: 21615493
DOI: 10.1111/j.1600-079X.2011.00902.x

Genes

ASMT
GPR50

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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