Article
Association analysis of the dopamine receptor D2 (DRD2) SNP rs1076560 in alcoholic patients.
Neuroscience letters - 29 Jan 2007
Sasabe Toshikazu, Furukawa Aizo, Matsusita Sachio, Higuchi Susumu, Ishiura Shoichi
Abstract excerpt
The dopamine system plays a well-established role in alcoholism. In this study, we examined the association between the single-nucleotide polymorphism (SNP) rs1076560 of the dopamine receptor D2 (DRD2) gene and susceptibility to alcoholism. SNP rs1076560 (C/A) is located in intron 6 of DRD2, where it is 1.4 kb downstream from alternative exon 6 and 83 bp upstream from exon 7. A total of 248 alcoholic patients and...
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