Article
Unique molecular signatures of Alzheimer's disease amyloid β peptide mutations and deletion during aggregate/oligomer/fibril formation.
Journal of neuroscience research - 1 Mar 2015
Poduslo Joseph F, Howell Kyle G
Abstract excerpt
The formation of amyloid β (Aβ) peptide aggregates, oligomers, and fibrils is a dynamic process; however, the kinetics of their formation is not well understood. This study compares the time course of aggregate/fibril formation by transmission electron microscopy (TEM) analyses with that of oligomer/fibril formation by Western blot analysis under native and denaturing conditions. Efforts to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
