Article
An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis.
Thrombosis and haemostasis - 1 Mar 2015
Marchetti Giovanna, Girelli Domenico, Zerbinati Carlotta, Lunghi Barbara, Friso Simonetta, Meneghetti Silvia, Coen Matteo, Gagliano Teresa, Guastella Giuseppe, Bochaton-Piallat Marie-Luce, Pizzolo Francesca, Mascoli Francesco, Malerba Giovanni, Bovolenta Matteo, Ferracin Manuela, Olivieri Oliviero, Bernardi Francesco, Martinelli Nicola
Abstract excerpt
Data with border-line statistical significance, copiously generated in genome-wide association studies of coronary artery disease (CAD), could include functionally relevant associations. We propose an integrated genomic and transcriptomic approach for unravelling new potential genetic signatures of atherosclerosis. Fifteen among 91 single nucleotide polymorphisms (SNPs) were first selected for association in a...
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