Article
Polymorphisms in fatty acid-binding protein-3 (FABP3) - putative association with type 2 diabetes mellitus.
Human mutation - 1 Aug 2003
Shin Hyoung Doo, Kim Lyoung Hyo, Park Byung Lae, Jung Hye Seung, Cho Young Min, Moon Min Kyong, Lee Hong Kyu, Park Kyong Soo
Abstract excerpt
Fatty acid-binding proteins (FABPs) play key roles as transport vehicles of fatty compounds throughout the cytoplasm. Human FABP3, one of the FABPs, is present in a wide variety of tissues with highest concentration in cardiac and skeletal muscle. In an effort to identify polymorphic markers in potential candidate genes for type 2 diabetes, we have sequenced the full gene of FABP3, including the -1,500bp promoter...
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