Article
The relative merits of cord blood as a cell source for autologous T regulatory cell therapy in type 1 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Jan 2015
Theil A, Wilhelm C, Guhr E, Reinhardt J, Bonifacio E
Abstract excerpt
Cord blood has been used as a cell source for therapeutic purposes in children with type 1 diabetes and other disorders. Here, we explore the benefits of cord blood as an autologous source of T regulatory cells for immune cell therapy in patients. CD4(+)CD25(+) T regulatory cells were isolated from cord blood and adult peripheral blood of healthy donors and compared during and after expansion in a 14-day protocol...
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