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Article

Functional characterization of 5-oxoproline transport via SLC16A1/MCT1.

The Journal of biological chemistry - 23 Jan 2015

Sasaki Shotaro, Futagi Yuya, Kobayashi Masaki, Ogura Jiro, Iseki Ken

Abstract excerpt

Thyrotropin-releasing hormone is a tripeptide that consists of 5-oxoproline, histidine, and proline. The peptide is rapidly metabolized by various enzymes. 5-Oxoproline is produced by enzymatic hydrolysis in a variety of peptides. Previous studies showed that 5-oxoproline could become a possible biomarker for autism spectrum disorders. Here we demonstrate the involvement of SLC16A1 in the transport of...

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Identifiers

PMID: 25371203
DOI: 10.1074/jbc.M114.581892
PMCID: PMC4303682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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