Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in the monocarboxylate transporter genes (SLC16A1, SLC16A3, and SLC16A11) in the Japanese population.

Drug metabolism and pharmacokinetics - 1 Oct 2018

Kimura Yuki, Kobayashi Masaki, Asari Masaru, Higuchi Issei, Narumi Katsuya, Furugen Ayako, Iseki Ken

Abstract excerpt

MCT1 (SLC16A1), MCT4 (SLC16A3), and MCT11 (SLC16A11) are members of the monocarboxylate transporter (MCT) family. MCT1 and MCT4 transport pH-related monocarboxylates, such as lactate and pyruvate. MCT11 may also be a proton-coupled monocarboxylate transporter. Although alterations of these substrates are involved in the pathology of cancer and diabetes, little is known about MCT polymorphisms. In this study,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Healthy Volunteers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monocarboxylic Acid Transporters

Share to Polymorphism, Genetic

Share to Symporters

Source

Identifiers

PMID: 30177396
DOI: 10.1016/j.dmpk.2018.05.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in the monocarboxylate transporter genes (SLC16A1, SLC16A3, and SLC16A11) in the Japanese population.PMID 30177396Read ↗

Genetic variations in the MCT1 (SLC16A1) gene in the Chinese population of Singapore.Semantic proximity Read ↗

Genetic variations of the MCT4 (SLC16A3) gene in the Chinese and Indian populations of Singapore.Semantic proximity Read ↗

The Association between the rs312457 Genotype of the SLC16a13 Gene and Diabetes Mellitus in a Chinese Population.Semantic proximity Read ↗

The association between SLC16A11 haplotype and lipid metabolism in Japanese patients with type 2 diabetes.Semantic proximity Read ↗

Genotype and Clinical Phenotype of Monocarboxylate Transporter 1 Deficiency in Three Palestinian Children: Report of Two Novel Variants in the SLC16A1 Gene.Semantic proximity Read ↗

Monocarboxylate transporters: past, present, and future.Semantic proximity Read ↗

SLC16A13 functions as a novel oncogenic driver in glioma by impairing monocarboxylate transport and mitochondrial redox homeostasisSemantic proximity Read ↗

Mct11 deficiency alters hepatic glucose metabolism and energy homeostasisSemantic proximity Read ↗

Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance.Semantic proximity Read ↗

The Tissue Expression of MCT3, MCT8, and MCT9 Genes in Women with Breast CancerSemantic proximity Read ↗

Functional characterization of 5-oxoproline transport via SLC16A1/MCT1.Semantic proximity Read ↗

Monocarboxylate transporter 1 deficiency and ketone utilization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.