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Article

Cholangiocarcinoma: molecular pathways and therapeutic opportunities.

Seminars in liver disease - 1 Nov 2014

Ilyas Sumera I, Borad Mitesh J, Patel Tushar, Gores Gregory J

Abstract excerpt

Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy with limited treatment options and low survival rates. Currently, there are no curative medical therapies for CCA. Recent advances have enhanced our understanding of the genetic basis of this disease, and elucidated therapeutically relevant targets. Therapeutic efforts in development are directed at several key pathways due to genetic aberrations...

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Source

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Identifiers

PMID: 25369307
DOI: 10.1055/s-0034-1394144
PMCID: PMC4294543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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