Article
T helper and B cell escape mutations within the HBc gene in patients with asymptomatic HBV infection: a study from the South-Eastern region of Iran.
Clinical laboratory - 1 Jan 2012
Assar Shokrollah, Arababadi Mohammad Kazemi, Mohit Maryam, Ahmadabadi Behzad Nasiri, Pumpens Paul, Khorramdelazad Hossein, Hajghani Masomeh, Assar Sepideh, Araste Majid, Nekhei Zohre, Sendi Hossein, Kennedy Derek
Abstract excerpt
BACKGROUND: Escape mutations potentially allow viruses to avoid detection and clearance by the host immune system and may represent a mechanism through which infections may persist in some patients. The association of the mutations in the HBcAg gene with Hepatitis B asymptomatic carriers (ASC) ha...
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