Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity.

PloS one - 1 Jan 2014

Wai Christine Y Y, Leung Nicki Y H, Ho Marco H K, Gershwin Laurel J, Shu Shang An, Leung Patrick S C, Chu Ka Hou

Abstract excerpt

Designer proteins deprived of its IgE-binding reactivity are being sought as a regimen for allergen-specific immunotherapy. Although shrimp tropomyosin (Met e 1) has long been identified as the major shellfish allergen, no immunotherapy is currently available. In this study, we aim at identifying the Met e 1 IgE epitopes for construction of hypoallergens and to determine the IgE inhibitory capacity of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allergens
Share to Antibody Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Food Hypersensitivity

Share to Immunization

Share to Immunoglobulin E

Share to Immunoglobulin G

Share to Penaeidae

Share to Tropomyosin

Source

Open in PubMed Open full text

Identifiers

PMID: 25365343
DOI: 10.1371/journal.pone.0111649
PMCID: PMC4218792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity.PMID 25365343Read ↗

Reduced allergenic potency of VR9-1, a mutant of the major shrimp allergen Pen a 1 (tropomyosin).Semantic proximity Read ↗

In Silico Prediction of Cross-Reactive Epitopes of Tropomyosin from Shrimp and Other Arthropods Involved in AllergySemantic proximity Read ↗

Determination of microheterogeneous substitution in shrimp tropomyosin and its effect on IgE-binding capacitySemantic proximity Read ↗

Seafood allergy and allergens: a review.Semantic proximity Read ↗

Analysis of the Allergenic Epitopes of Tropomyosin from Mud Crab Using Phage Display and Site-Directed MutagenesisSemantic proximity Read ↗

Toward Consensus Epitopes B and T of Tropomyosin Involved in Cross-Reactivity across Diverse Allergens: An In Silico StudySemantic proximity Read ↗

Homologous tropomyosins from vertebrate and invertebrate: Recombinant calibrator proteins in functional biological assays for tropomyosin allergenicity assessment of novel animal foodsSemantic proximity Read ↗

Reduction of allergenic properties of shrimp (Penaeus Vannamei) allergens by high intensity ultrasoundSemantic proximity Read ↗

Tropomyosin: A panallergen that causes a worldwide allergic problemSemantic proximity Read ↗

In silico Identification of IgE-Binding Epitopes of Osmotin ProteinSemantic proximity Read ↗

Engineered hypoallergenic variants of osmotin demonstrate hypoallergenicity with in vitro and in vivo methods.Semantic proximity Read ↗

Designing a Hypoallergenic Mutant of Cra a 2 with T-Cell Reactivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.