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Article

In silico Identification of IgE-Binding Epitopes of Osmotin Protein

18 Jan 2013

Abstract excerpt

The identification of B-cell epitopes is an important step to study the antigen- antibody interactions for diagnosis and therapy. The present study aimed to identify B- cell epitopes of osmotin using bioinformatic tools and further modify these regions to study the allergenic property. B-cell epitopes were predicted based on amino acid physicochemical properties. Three single point mutations M1, M2, and M3 and a...

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PMID: 23349964
DOI: 10.1371/journal.pone.0054755

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