Article
Genetics and epigenetics of Alzheimer's disease.
Postgraduate medical journal - 1 Sept 2012
Alagiakrishnan Kannayiram, Gill Sudeep S, Fagarasanu Andrei
Abstract excerpt
Alzheimer's disease (AD) is a highly prevalent condition that predominantly affects older adults. AD is a complex multifactorial disorder with a number of genetic, epigenetic and environmental factors which ultimately lead to premature neuronal death. Predictive and susceptibility genes play a role in AD. Early-onset familial AD is a rare autosomal dominant disorder. Genome-wide association studies have...
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