Article
Association of E-cadherin single-nucleotide polymorphisms with the increased risk of breast cancer: a study in South Indian women.
Genetic testing and molecular biomarkers - 1 Jun 2013
Tipirisetti Nageswara Rao, Govatati Suresh, Govatati Sowdamani, Kandukuri Lakshmi Rao, Cingeetham Anuradha, Singh Lalji, Digumarti Raghunadha Rao, Bhanoori Manjula, Satti Vishnupriya
Abstract excerpt
BACKGROUND: E-cadherin (CDH1) plays an important role in intercellular adhesion, cell signaling, and cellular differentiation. Association of single-nucleotide polymorphisms (SNPs) of CDH1 has been identified in a number of epithelial malignancies; however, studies related to breast cancer are very few. AIM: To investigate the association between CDH1 SNPs and breast cancer risk in south Indian women. METHODS:...
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