Article
HNF1A gene polymorphisms and cardiovascular risk factors in individuals with late-onset autosomal dominant diabetes: a cross-sectional study.
Cardiovascular diabetology - 2 Jun 2009
Giuffrida Fernando M A, Furuzawa Gilberto K, Kasamatsu Teresa S, Oliveira Marcos M, Reis Andre F, Dib Sergio A
Abstract excerpt
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a genetically heterogeneous disease, hepatocyte nuclear factor-1 homeobox A (HNF1A) single-nucleotide polymorphisms (SNPs) playing a minor role in its pathogenesis. HNF1A is a frequent cause of monogenic diabetes, albeit with early-onset. Some uncommon subgroups like late-onset autosomal dominant diabetes mellitus (LOADDM) may present peculiar inheritance patterns...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
