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Article

Identification of novel GCK and HNF1A/TCF1 mutations and polymorphisms in German families with maturity-onset diabetes of the young (MODY).

Human mutation - 1 May 2005

Toaima Dalia, Näke Andrea, Wendenburg Jutta, Praedicow Kirsten, Rohayem Julia, Engel Kerstin, Galler Angela, Gahr Manfred, Lee-Kirsch Min Ae

Abstract excerpt

Maturity-onset diabetes of the young is a genetically heterogeneous autosomal dominant form of diabetes mellitus, characterized by an early age at onset and a primary defect in beta-cell function. Forty families with a clinical presentation suggestive of MODY were screened for the most common MODY subtypes caused by mutations in the genes encoding glucokinase (GCK, MODY2) and hepatocyte nuclear 1-alpha...

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Source

Identifiers

PMID: 15841481
DOI: 10.1002/humu.9334

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of novel GCK and HNF1A/TCF1 mutations and polymorphisms in German families with maturity-onset diabetes of the young (MODY).PMID 15841481Read ↗

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