Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HNF1alpha mutations are present in half of clinically defined MODY patients in South-Brazilian individuals.

Arquivos brasileiros de endocrinologia e metabologia - 1 Nov 2008

Maraschin Jorge de Faria, Kannengiesser Caroline, Murussi Nádia, Campagnolo Nicole, Canani Luís Henrique, Gross Jorge Luiz, Velho Gilberto, Grandchamp Bernard, Silveiro Sandra Pinho

Abstract excerpt

Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes mellitus characterized by autosomal dominant inheritance, early age of onset, and pancreatic beta cell dysfunction. Heterozygous mutations in at least seven genes can cause MODY. In the present study we investigated the r...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucokinase

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Heterozygote

Share to Pedigree

Share to Prevalence

Share to Young Adult

Source

Identifiers

PMID: 19169489
DOI: 10.1590/s0004-27302008000800020

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19169489-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HNF1alpha mutations are present in half of clinically defined MODY patients in South-Brazilian individuals.PMID 19169489Read ↗

Clinical application of ACMG-AMP guidelines in HNF1A and GCK variants in a cohort of MODY families.Semantic proximity Read ↗

Identification of novel GCK and HNF1A/TCF1 mutations and polymorphisms in German families with maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Maturity-Onset Diabetes of the Young (MODY) in Portugal: Novel GCK, HNFA1 and HNFA4 MutationsSemantic proximity Read ↗

GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY).Semantic proximity Read ↗

Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young.Semantic proximity Read ↗

Update on clinical screening of maturity-onset diabetes of the young (MODY)Semantic proximity Read ↗

Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Hyperglycemia Due to HNF1A-Mutation-Associated Maturity-Onset Diabetes of the Young (MODY) in a 6-Year-Old Kazakh Girl.Semantic proximity Read ↗

Mutations in GCK and HNF-1alpha explain the majority of cases with clinical diagnosis of MODY in Spain.Semantic proximity Read ↗

Maturity-onset diabetes of the young (MODY): an update.Semantic proximity Read ↗

Nine novel mutations in maturity-onset diabetes of the young (MODY) candidate genes in 22 Spanish families.Semantic proximity Read ↗

The spectrum of HNF1A gene mutations in Greek patients with MODY3: relative frequency and identification of seven novel germline mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.