Article
High plasma levels of heparin-binding epidermal growth factor are associated with a more stable plaque phenotype and reduced incidence of coronary events.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2015
Rattik Sara, Wigren Maria, Björkbacka Harry, Fredrikson Gunilla Nordin, Hedblad Bo, Siegbahn Agneta, Bengtsson Eva, Schiopu Alexandru, Edsfeldt Andreas, Dunér Pontus, Grufman Helena, Gonçalves Isabel, Nilsson Jan
Abstract excerpt
OBJECTIVE: Rupture of atherosclerotic plaques is the major cause of acute coronary events (CEs). Plaque destabilization is the consequence of an imbalance between inflammatory-driven degradation of fibrous tissue and smooth muscle cell-dependent tissue repair. Proinflammatory factors have been documented extensively as biomarkers of cardiovascular risk but factors that contribute to stabilization of...
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