Article

N-Terminal proteomics reveals distinct protein degradation patterns in different types of human atherosclerotic plaques

2024-05-18

Abstract excerpt

<h4>BACKGROUND</h4> Destabilization and rupture of atherosclerotic plaques is a major cause of acute atherosclerotic cardiovascular events, including heart attack, ischemic stroke and peripheral arterial disease. Plaque destabilization is associated with extracellular matrix (ECM) modification and remodelling involving protease activity. Enzymatic cleavage generates protein fragments with new ‘ends’ (N-termini)....

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Literature Corpus work: 7d5c7999-f7a3-5741-9cd7-7f950ba428f0
DOI: 10.1101/2024.05.14.594251

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