Article

Monocyte-chemoattractant protein-1 Levels in Human Atherosclerosis Associate with Plaque Vulnerability

2020-09-05

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) recruits monocytes to the atherosclerotic plaque. While experimental, 1–6 genetic, 7 and observational 8,9 data support a key role of MCP-1 in atherosclerosis, the translational potential of targeting MCP-1 signaling for lowering vascular risk is limited by the lack of data on plaque MCP-1 activity in human atherosclerosis. Here, we measured MCP-1 levels in human plaque s...

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Literature Corpus work: 043607a9-58dd-5087-980f-f4fd7138f72b
DOI: 10.1101/2020.09.04.20187955

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