Article
Plasma C-reactive protein is associated with a pro-inflammatory and adverse plaque phenotype.
Atherosclerosis - 1 Sept 2024
Kraaijenhof Jordan M, Mol Barend M, Nurmohamed Nick S, Dzobo Kim E, Kroon Jeffrey, Hovingh G Kees, Mokry Michal, de Borst Gert J, Stroes Erik S G, de Kleijn Dominique P V
Abstract excerpt
BACKGROUND AND AIMS: Systemic low-grade inflammation, measured by plasma high-sensitivity C-reactive protein (hsCRP) levels, is an important risk factor for atherosclerotic cardiovascular disease (ASCVD). To date, however, it is unknown whether plasma hsCRP is associated with adverse histological plaque features. METHODS: Plaques were derived during carotid endarterectomy. Patients with hsCRP levels ≥2 mg/L were...
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