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Article

IL10 rs1800896 Genetic Variant Predicts Biochemical Remission in Inflammatory Bowel Disease Patients Undergoing Biologic Therapy.

Immunology - 1 Feb 2026

Falzone Michela Helga, Ribaldone Davide Giuseppe, Buglione Martina, Cottone Irene, Vernero Marta, Pitoni Demis, Armandi Angelo, Saba Francesca, Dileo Eleonora, Santovito Alfredo, Caviglia Gian Paolo

Abstract excerpt

Genetic factors, including single-nucleotide variants (SNVs), may modulate disease course and therapeutic efficacy in patients with inflammatory bowel disease (IBD). We investigated the association between four SNVs in cytokine genes and clinical phenotype as well as the response to molecular-targeted drugs in patients with IBD. A total of 197 IBD patients (142 Crohn's disease [CD], 55 ulcerative colitis [UC])...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41163119
DOI: 10.1111/imm.70058

Genes

IL10
IL6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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