Article
Cytokine gene polymorphisms in irritable bowel syndrome in Indian population--a pilot case control study.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation - 1 Jan 2000
Santhosh S, Dutta A K, Samuel P, Joseph A J, Ashok Kumar J, Kurian George
Abstract excerpt
AIM: This study aimed at evaluating the single nucleotide polymorphisms (SNPs) in five cytokine genes regulating inflammation at altogether 8 different loci and compared their frequencies in patients with Irritable bowel syndrome (IBS) versus healthy age and sex matched controls. METHODS: Peripheral blood was collected for DNA cytokine analysis from 23 patients with lBS and 20 healthy controls. The cytokine SNPs...
Topics
- Alleles
- Case-Control Studies
- Chi-Square Distribution
- Female
- Genotype
- Humans
- India
- Interferon-alpha
- Interleukin-10
- Interleukin-6
- Irritable Bowel Syndrome
