Article
Identified single-nucleotide polymorphisms and haplotypes at 16q22.1 increase diabetic nephropathy risk in Han Chinese population.
BMC genetics - 31 Oct 2014
Liao Li-Na, Chen Ching-Chu, Wu Fang-Yang, Lin Cheng-Chieh, Hsiao Jen-Hao, Chang Chwen-Tzuei, Kardia Sharon L R, Li Tsai-Chung, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: Diabetic nephropathy (DN) has become one of the most common causes of end-stage renal disease (ESRD) in many countries, such as 44.5% in Taiwan. Previous studies have shown that there is a genetic component to ESRD. Studies attempting to determine which genetic variants are related to DN in Han Chinese are limited. A case-control study was conducted to identify DN susceptibility variants in Han...
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