Article
Risk prediction of nephropathy by integrating clinical and genetic information among adult patients with type 2 diabetes.
Acta diabetologica - 1 Mar 2023
Liao Li-Na, Li Tsai-Chung, Yeh Chih-Ching, Li Chia-Ing, Liu Chiu-Shong, Yang Chuan-Wei, Yang Ya-Fei, Lin Chih-Hsueh, Tsai Fuu-Jen, Lin Cheng-Chieh
Abstract excerpt
AIMS: Diabetic nephropathy (DN) is a major healthcare challenge. We developed and internally and externally validated a risk prediction model of DN by integrating clinical factors and SNPs from genes of multiple CKD-related pathways in the Han Chinese population. MATERIALS AND METHODS: A total of 1526 patients with type 2 diabetes were randomly allocated into derivation (n = 1019) or validation (n = 507) sets....
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