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Article

Identification of novel genomic variants in diabetic nephropathy patients using whole-exome sequencing: a pilot investigation.

Frontiers in endocrinology - 1 Jan 2026

Mir Rashid, Elfaki Imadeldin, Almassabi Rehab F, Almowallad Sanaa, Elnageeb Mohamed E, Mirghani Hyder Osman, Albalawi Wed, Albalawi Aziz Dhaher, Altemani Faisal H, Barnawi Jameel, Tayeb Faris J, Moawadh Mamdoh, Bedaiwi Ruqaiah I, Alanazi Mohammad A

Abstract excerpt

Background: Type 2 diabetes (T2D) is a challenge for the healthcare system. It is a metabolic disease with increased blood sugar with severe complications when it becomes uncontrolled. These complications include diabetic nephropathy (DN), neuropathy, retinopathy neuropathy, and cardiovascular diseases (CVDs). T2D is induced by genetic, environmental, and lifestyle risk factors. Therefore, it is vital to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41970998
DOI: 10.3389/fendo.2026.1798640
PMCID: PMC13062162

Genes

PBX2
PHKG2
SRCAP
TNFRSF6B
ARFGEF2
CDH3
CRHR1
INSR
NOTCH4
SP2
TNXB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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