Article
Integrated Transcriptomic-Proteomic Analysis Using a Proteogenomic Workflow Refines Rat Genome Annotation.
Molecular & cellular proteomics : MCP - 1 Jan 2016
Kumar Dhirendra, Yadav Amit Kumar, Jia Xinying, Mulvenna Jason, Dash Debasis
Abstract excerpt
Proteogenomic re-annotation and mRNA splicing information can lead to the discovery of various protein forms for eukaryotic model organisms like rat. However, detection of novel proteoforms using mass spectrometry proteomics data remains a formidable challenge. We developed EuGenoSuite, an open source multiple algorithmic proteomic search tool and utilized it in our in-house integrated transcriptomic-proteomic...
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