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Article

Establishment of a Langerhans cell histiocytosis lesion cell line with dermal dendritic cell characteristics.

Oncology reports - 1 Jan 2015

Murakami Ichiro, Gogusev Jean, Jaubert Francis, Matsushita Michiko, Hayashi Kazuhiko, Miura Ikuo, Tanaka Takehiro, Oka Takashi, Yoshino Tadashi

Abstract excerpt

A cell line named PRU-1, derived from a Langerhans cell (LC) histiocytosis (LCH) skull lesion of a 7-year-old boy, was established and characterized. PRU-1 is an adherent spindle-shaped cell line that shows no Birbeck granules on electron microscopy. Flow cytometric analysis of cells collected from the early seventh passage showed no LC phenotypes of CD1a and S100 protein. Immunostaining of PRU-1 cells also...

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Identifiers

PMID: 25351656
DOI: 10.3892/or.2014.3567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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