Article
Cytokine gene polymorphisms, cytokine levels and the risk of colorectal neoplasia in a screened population of Northeast Scotland.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Jul 2015
Basavaraju Umesh, Shebl Fatma M, Palmer Andrew J, Berry Susan, Hold Georgina L, El-Omar Emad M, Rabkin Charles S
Abstract excerpt
Cytokine gene polymorphisms modify expression and their circulating protein levels reflect inflammatory response. Chronic inflammation plays a key role in the pathogenesis of colorectal neoplasia (CRN) associated with inflammatory bowel disease, but it is not clear whether inflammation is a cause or an effect of tumours in sporadic CRN. We therefore investigated the association of cytokine gene polymorphisms and...
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