Article
Cystic fibrosis airway epithelium remodelling: involvement of inflammation.
The Journal of pathology - 1 Feb 2015
Adam Damien, Roux-Delrieu Jacqueline, Luczka Emilie, Bonnomet Arnaud, Lesage Julien, Mérol Jean-Claude, Polette Myriam, Abély Michel, Coraux Christelle
Abstract excerpt
Chronic inflammation is a hallmark of cystic fibrosis (CF) lung disease and airway epithelium damage and remodelling are important components of lung pathology progression in CF. Whether this remodelling is secondary to deleterious infectious and inflammatory mediators, or to alterations of CF human airway epithelial (HAE) cells, such as their hyper inflammatory phenotype or their basic cystic fibrosis...
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