Article
Reconstituted human upper airway epithelium as 3-d in vitro model for nasal polyposis.
PloS one - 1 Jan 2014
de Borja Callejas Francisco, Martínez-Antón Asunción, Alobid Isam, Fuentes Mireya, Cortijo Julio, Picado César, Roca-Ferrer Jordi, Mullol Joaquim
Abstract excerpt
BACKGROUND: Primary human airway epithelial cells cultured in an air-liquid interface (ALI) develop a well-differentiated epithelium. However, neither characterization of mucociliar differentiation overtime nor the inflammatory function of reconstituted nasal polyp (NP) epithelia have been described. OBJECTIVES: 1st) To develop and characterize the mucociliar differentiation overtime of human epithelial cells of...
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