Article
Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease--an association study and expression analysis.
Autoimmunity - 1 Mar 2015
Fichna Marta, Żurawek Magdalena, Bratland Eirik, Husebye Eystein S, Kasperlik-Załuska Anna, Czarnocka Barbara, Januszkiewicz-Lewandowska Danuta, Nowak Jerzy
Abstract excerpt
Autoimmune Addison's disease (AAD) results from T cell-mediated destruction of the adrenal cortex, commonly accompanied by autoantibodies to 21-hydroxylase (21OH). In order to gain insight into the obscure aetiology of this disease, we investigated the roles of the IL2 and IL2RA genes, encoding i...
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