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Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease--an association study and expression analysis.

Autoimmunity - 1 Mar 2015

Fichna Marta, Żurawek Magdalena, Bratland Eirik, Husebye Eystein S, Kasperlik-Załuska Anna, Czarnocka Barbara, Januszkiewicz-Lewandowska Danuta, Nowak Jerzy

Abstract excerpt

Autoimmune Addison's disease (AAD) results from T cell-mediated destruction of the adrenal cortex, commonly accompanied by autoantibodies to 21-hydroxylase (21OH). In order to gain insight into the obscure aetiology of this disease, we investigated the roles of the IL2 and IL2RA genes, encoding interleukin-2 and subunit alpha of its receptor (IL2Ra), respectively. The association of AAD with IL2 and IL2RA...

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Identifiers

PMID: 25347332
DOI: 10.3109/08916934.2014.976628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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