MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency.

doi:10.1210/jc.2006-0855

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Article

MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency.

The Journal of clinical endocrinology and metabolism - 1 Oct 2006

Ghaderi Mehran, Gambelunghe Giovanni, Tortoioli Cristina, Brozzetti Annalisa, Jatta Ken, Gharizadeh Baback, De Bellis Annamaria, Pecori Giraldi Francesca, Terzolo Massimo, Betterle Corrado, Falorni Alberto

Abstract excerpt

CONTEXT: The polymorphism of class II HLA genes modulates the genetic risk for several endocrine autoimmune diseases. The constitutive class II expression on antigen-presenting cells is under the control of the MHC class II transactivator, encoded by the MHC2TA gene, which is mapped to chromosome 16p13. The MHC2TA -168 A-->G single nucleotide polymorphism (rs3087456) has been suggested to confer susceptibility to...

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Identifiers

PMID: 16849401
DOI: 10.1210/jc.2006-0855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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