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Article

Role of the ρ1 GABA(C) receptor N-terminus in assembly, trafficking and function.

ACS chemical neuroscience - 17 Dec 2014

Wong Lik-Wei, Tae Han-Shen, Cromer Brett A

Abstract excerpt

The GABAC receptor and closely related GABAA receptor are members of the pentameric ligand-gated ion channels (pLGICs) superfamily and mediate inhibitory fast synaptic transmission in the nervous system. Each pLGIC subunit comprises an N-terminal extracellular agonist-binding domain followed by a channel domain and a variable intracellular domain. Available structural information shows that the core of the...

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Identifiers

PMID: 25347026
DOI: 10.1021/cn500220t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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