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Article

Association between genetic polymorphisms of the β1-adrenergic receptor and sensitivity to pain and fentanyl in patients undergoing painful cosmetic surgery.

Journal of pharmacological sciences - 1 Jan 2013

Moriyama Ayako, Nishizawa Daisuke, Kasai Shinya, Hasegawa Junko, Fukuda Ken-ichi, Nagashima Makoto, Katoh Ryoji, Ikeda Kazutaka

Abstract excerpt

Individual differences in the sensitivity to fentanyl, a widely used opioid analgesic, can hamper effective pain treatment. The adrenergic system is reportedly involved in the mechanisms of pain and analgesia. Here, we focused on one of the adrenergic receptor genes, ADRB1, and analyzed the influence of single-nucleotide polymorphisms (SNPs) in the ADRB1 gene on individual differences in pain and analgesic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pain, Postoperative

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Share to Receptors, Adrenergic, beta-1

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Source

Identifiers

PMID: 23257656
DOI: 10.1254/jphs.12159fp

Genes

ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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