Article
Erythroid band 3 variants and disease.
Bailliere's best practice & research. Clinical haematology - 1 Dec 1999
Bruce L J, Tanner M J
Abstract excerpt
This review describes some of the naturally occurring band 3 (AEI) variants and their association with disease. Southeast Asian Ovalocytic (SAO) band 3, an inactive and misfolded protein, is probably only maintained in certain populations because it provides protection against the cerebral form of malaria. Many mutations that cause instability of band 3, either at the mRNA or protein level, result in hereditary...
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