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Article

Epiprofin orchestrates epidermal keratinocyte proliferation and differentiation

1 Jan 2014

Abstract excerpt

The basal layer of the epidermis contains stem cells and transit amplifying cells that rapidly proliferate and differentiate further into the upper layers of the epidermis. A number of molecules have been identified as regulators of this process, including p63 (also known as tumor protein 63) and Notch1. However, little is known about the mechanisms that regulate the transitions from stem cell to proliferating or...

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PMID: 25344255
DOI: 10.1242/jcs.156778

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