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Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators

1 Jan 2020

Abstract excerpt

Keratinocyte is the predominant cell type in the epidermis of skin, and it provides the protective barrier function for the body. Various signaling pathways have been implicated in keratinocyte differentiation in animal models; However, their temporal regulation and interactions are still to be explored in pluripotent stem cell models. In this report, we use human embryonic stem cells to demonstrate that...

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PMID: 32210732
DOI: 10.7150/ijbs.44414

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