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Genetics pathway-based imaging approaches in Chinese Han population with Alzheimer's disease risk.

Brain structure & function - 1 Jan 2016

Bai Feng, Liao Wei, Yue Chunxian, Pu Mengjia, Shi Yongmei, Yu Hui, Yuan Yonggui, Geng Leiyu, Zhang Zhijun

Abstract excerpt

The tau hypothesis has been raised with regard to the pathophysiology of Alzheimer's disease (AD). Mild cognitive impairment (MCI) is associated with a high risk for developing AD. However, no study has directly examined the brain topological alterations based on combined effects of tau protein pathway genes in MCI population. Forty-three patients with MCI and 30 healthy controls underwent resting-state...

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PMID: 25344117
DOI: 10.1007/s00429-014-0916-4

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