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Article

The role of genome sequencing in personalized breast cancer prevention.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2014

Sieh Weiva, Rothstein Joseph H, McGuire Valerie, Whittemore Alice S

Abstract excerpt

BACKGROUND: There is uncertainty about the benefits of using genome-wide sequencing to implement personalized preventive strategies at the population level, with some projections suggesting little benefit. We used data for all currently known breast cancer susceptibility variants to assess the benefits and harms of targeting preventive efforts to a population subgroup at highest genomic risk of breast cancer....

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PMID: 25342391
DOI: 10.1158/1055-9965.EPI-14-0559
PMCID: PMC4221442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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