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Article

Prognostic value of CTNNB1 gene mutation in primary sporadic aggressive fibromatosis.

Annals of surgical oncology - 1 May 2015

van Broekhoven Danique L M, Verhoef Cornelis, Grünhagen Dirk J, van Gorp Joost M H H, den Bakker Michael A, Hinrichs John W J, de Voijs Carmen M A, van Dalen Thijs

Abstract excerpt

BACKGROUND: Aggressive fibromatosis (AF) comprises tumors with a varying biological behavior. Genetic tumor characteristics may be predictive of recurrence; hence, the prognostic value of three specific mutations on the CTNNB1 gene was evaluated in relation to known clinicopathologic risk factors in patients with primary, sporadic AF. METHODS: In a multi-institutional retrospective cohort study of patients with...

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Identifiers

PMID: 25341748
DOI: 10.1245/s10434-014-4156-x

Genes

CTNNB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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