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Article

Mucuna pruriens (Velvet bean) rescues motor, olfactory, mitochondrial and synaptic impairment in PINK1B9 Drosophila melanogaster genetic model of Parkinson's disease.

PloS one - 1 Jan 2014

Poddighe Simone, De Rose Francescaelena, Marotta Roberto, Ruffilli Roberta, Fanti Maura, Secci Pietro Paolo, Mostallino Maria Cristina, Setzu Maria Dolores, Zuncheddu Maria Antonietta, Collu Ignazio, Solla Paolo, Marrosu Francesco, Kasture Sanjay, Acquas Elio, Liscia Anna

Abstract excerpt

The fruit fly Drosophila melanogaster (Dm) mutant for PTEN-induced putative kinase 1 (PINK1B9) gene is a powerful tool to investigate physiopathology of Parkinson's disease (PD). Using PINK1B9 mutant Dm we sought to explore the effects of Mucuna pruriens methanolic extract (Mpe), a L-Dopa-contain...

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Identifiers

PMID: 25340511
DOI: 10.1371/journal.pone.0110802
PMCID: PMC4207759

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25340511-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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