Article
Impaired sense of smell in a Drosophila Parkinson's model.
PloS one - 1 Jan 2013
Poddighe Simone, Bhat Krishna Moorthi, Setzu Maria Dolores, Solla Paolo, Angioy Anna Maria, Marotta Roberto, Ruffilli Roberta, Marrosu Francesco, Liscia Anna
Abstract excerpt
Parkinson's disease (PD) is one of the most common neurodegenerative disease characterized by the clinical triad: tremor, akinesia and rigidity. Several studies have suggested that PD patients show disturbances in olfaction at the earliest onset of the disease. The fruit fly Drosophila melanogaster is becoming a powerful model organism to study neurodegenerative diseases. We sought to use this system to explore...
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