Article
[The role of intraperitoneal macrophages in the progression of peritoneal carcinomatosis from gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Oct 2014
Yamaguchi Takahisa, Fushida Sachio, Tsukada Tomoya, Kinoshita Jun, Oyama Katsunobu, Watanabe Toshifumi, Okamoto Koichi, Nakamura Keishi, Ninomiya Itasu, Fujimura Takashi, Ohta Tetsuo
Abstract excerpt
Tumor-associated macrophages(TAM)of the M2 phenotype(M2 macrophage)promote tumor proliferation and are associated with a poor prognosis in several tumors. We investigated the phenotype of macrophages in gastric cancer patients with peritoneal carcinomatosis(PC). Intraperitoneal macrophages were found more frequently in PC patients than in Stage I or II patients(control). CD163, an M2 macrophage surface marker,...
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