Article
Novel adeno-associated viruses derived from pig tissues transduce most major organs in mice.
Scientific reports - 22 Oct 2014
Bello Alexander, Chand Allan, Aviles Jenna, Soule Geoff, Auricchio Alberto, Kobinger Gary P
Abstract excerpt
Recently, development of Adeno-associated virus (AAV) vectors has been focusing on expanding the genetic diversity of vectors from existing sequences via directed evolution or epitope remapping. Apart from intelligent design, AAV isolation from natural sources remains an important source of new AAVs with unique biological features. In this study, several new AAV sequences were isolated from porcine tissues...
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