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Article

Chemically induced mouse liver tumors are resistant to treatment with atorvastatin.

BMC cancer - 15 Oct 2014

Braeuning Albert, Bucher Philip, Hofmann Ute, Buchmann Albrecht, Schwarz Michael

Abstract excerpt

BACKGROUND: Atorvastatin is a potent inhibitor of the mevalonate pathway and widely used as a hypolipidemic drug. Some epidemiological studies and animal experiments indicate that the long-term use of atorvastatin and structurally related drugs might be associated with a reduced risk of developing hepatocellular carcinoma (HCC), the most common hepatocellular malignancy in humans. However, the potential of...

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Identifiers

PMID: 25319454
DOI: 10.1186/1471-2407-14-766
PMCID: PMC4203962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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