Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alzheimer Amyloid Peptide Aβ42 Regulates Gene Expression of Transcription and Growth Factors

22 Jan 2015

Abstract excerpt

The pathogenesis of Alzheimer's disease (AD) is characterized by the aggregation of amyloid-β (Aβ) peptides leading to deposition of senile plaques and a progressive decline of cognitive functions, which currently remains the main criterion for its diagnosis. Robust biomarkers for AD do not yet exist, although changes in the cerebrospinal fluid levels of tau and Aβ represent promising candidates in addition to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Bone Metabolism and Diseases
Share to Dementia and Cognitive Impairment Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25318543
DOI: 10.3233/jad-141902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alzheimer Amyloid Peptide Aβ42 Regulates Gene Expression of Transcription and Growth FactorsPMID 25318543Read ↗

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.Semantic proximity Read ↗

Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkersSemantic proximity Read ↗

Targeting Alzheimer's disease with gene and cell therapiesSemantic proximity Read ↗

Genome-wide RNA sequencing analysis reveals that IGF-2 attenuates memory decline, oxidative stress and amyloid plaques in an Alzheimer’s disease mouse model (AD) by activating the PI3K/AKT/CREB signaling pathwaySemantic proximity Read ↗

The emerging role of microRNA-4487/6845-3p in Alzheimer’s disease pathologies is induced by Aβ25–35 triggered in SH-SY5Y cellSemantic proximity Read ↗

Behavioural effects and RNA-seq analysis of Aβ42 mediated toxicity in a Drosophila Alzheimer’s disease modelSemantic proximity Read ↗

<i>HnRNPAB</i> -targeted antisense oligonucleotides ameliorate tau pathology and cognitive deficits by modulating Alzheimer’s disease-associated alternative splicingSemantic proximity Read ↗

Molecular pathogenesis of sporadic and familial forms of Alzheimer's disease.Semantic proximity Read ↗

Integrative Human Genetic and Cellular Analysis of the Pathophysiological Roles of AnxA2 in Alzheimer’s DiseaseSemantic proximity Read ↗

Identification of the Role of miR-142-5p in Alzheimer’s Disease by Comparative Bioinformatics and Cellular AnalysisSemantic proximity Read ↗

C/ EBPβ : A transcription factor associated with the irreversible progression of Alzheimer's diseaseSemantic proximity Read ↗

Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.