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Article

Identification of the Role of miR-142-5p in Alzheimer’s Disease by Comparative Bioinformatics and Cellular Analysis

18 Jul 2017

Abstract excerpt

Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by the formation of amyloid beta (Aβ) or tau protein aggregates, the hallmark of cognitive decline. MicroRNAs (miRNAs) have emerged as critical factors in neurogenesis and synaptic functions in the central nervous system. Recent studies have reported alterations in miRNA expression in patients with AD. However, miRNAs associated...

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PMID: 28769761
DOI: 10.3389/fnmol.2017.00227

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